Tetrahydrothiopyran-4-one as Five-Carbon Source for Scalable Synthesis of (±)-Tapentadol
Ramagonolla Kranthikumar
- Prathama S. Mainkar
- Genji Sukumar
- Rambabu Chegondi
- Srivari Chandrasekhar*
The improved process for the synthesis of (±)-tapentadol, the FDA-approved analgesic drug, is achieved from tetrahydrothiopyran-4-one as the five-carbon source.
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