Polymer-based Solid Phase Extraction Products
Orochem synthesizes a full range of polymer-based, solid phase extraction (SPE) sorbents. Every sorbent batch must pass a series of quality control tests to ensure batch-to-batch reproducibility and performance. Orochem’s Panthera Deluxe and Agility Deluxe products provide high performance at an affordable price. Sorbents are available in cartridges, 96-well plates, and microelute plate format. Combined method development 96-well plates can be custom made upon request.
Panthera Deluxe Polymeric SPE Products
The Panthera Deluxe sorbent is based on poly-DVB and provides both hydrophobic and hydrophilic retention. It demonstrates high capacity and retention for a full range of neutral, basic, and acidic compounds and is particularly suitable for pain management drugs and other pharmaceuticals.
Technical Specifications:
Mode: Reversed phase
Average Particle Size: 15 µm
Average Pore Size: 39 Å
Sorbent Substrate: Polymeric DVB
Water Wettable: Yes
Mass Spec Compatible: Yes
pH Range: 0-14
Orochem customers have used Panthera Deluxe to separate the following examples in various matrices:
- Reloxifene
- Albendazole
- Topiramate
- Pregabalin
- Dolutegravir
- Dapagliflozine
- Ibuprofen
- Loratidine
- Bile Acids
- Paliperidon
- Sofosbuuvir
- Chlorozoxazone
- Pramipexole
- Hydroxychloroquine
- Isosorbide Mononitrate
- Bupivacaine Liposomal
- Amphotericine B Liposomal
General Extraction Method
(based on 30 mg/cc cartridge)
Stationary phase: Reversed phase
(Panthera Deluxe )
Condition(optional): 1 ml of methanol followed by 1 ml of water
Loading step: 0.1-0.5 ml of plasma or other sample
Washing step: 1 ml of water followed by 1 ml of 5% methanol (depending on analyte)
Elution step: 1 ml of methanol (depending on analyte, other common solvents are acetonitrile, ethanol)
A PRESENTATION
Established in 1996, Orochem Technologies Inc. started as a Biotech and Chromatography company to manufacture unique Sample Prep Technology “Products” for the Bioanalysis, Drug Discovery, and the Genomics and Proteomics markets.
Established in 1996, Orochem Technologies Inc. started as a Biotech and Chromatography company to manufacture unique Sample Prep Technology Products for the Bioanalysis, Drug Discovery, and the Genomics and Proteomics markets. Backed with unique expertise in high throughput formats, membranes and surface chemistries, Orochem was one of the first companies to translate the concept of pre-filters from single to high throughput formats, a concept now widely implemented for sample prep plates in the biotech and analytical markets. In the year 2001 Orochem manufactured the first commercially available Protein Crash and Precipitation 96-well plate for Bioanalytical processes. By the year 2006, with the acquisition of Column Engineering Inc, Orochem evolved to become a “full-service” provider for silica manufacturing utilized for analytical and preparatory chromatography. Orochem invests heavily into R&D in-house and owns strong intellectual property in stationary phases for achiral and Chiral Chromatography.
Orochem’s is globally recognized as an organization that conceives, develops, and installs some of the most technologically viable solutions for “highest purities” for industrial or “metric ton” scale purification for API’s, nutritional supplements, fatty acids, and specialty sugars. Orochem provides Simulated Moving Bed (SMB) Chromatography technology for the laboratory scale, pilot scale and large-scale purification of commercially viable molecules for its customers around the world. Orochem’s products and services for Simulated Moving Bed Chromatography include Synthesis and manufacture of stationary phases “tailored for specific separations”, a uniquely engineered SMB system and the installation and commissioning of the SMB systems at customer sites with well-trained Orochem technical service engineers.
Orochem owns several manufacturing facilities around the world. The Naperville, Illinois, USA site has about 84,000 square feet of manufacturing area where most of the Membrane Filter Plates, Silica manufacturing, Silica bonding, Solid Phase Extraction products and HPLC Columns are manufactured. Orochem India, Mumbai has 20,000 square feet facility and manufactures Sample prep products for the Discovery & Clinical Research organizations in Asia. Simulated Moving Bed chromatography systems are designed, built and assembled completely at our US locations in Naperville in Illinois.
USA (HQ)
Orochem Technologies Inc.
630 210 8300
630 210 8315
info@orochem.com
340 Shuman Blvd., Naperville, 60563, IL.
Orochem Molecular Purification by Design
https://orochem.com/
