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The diastereoselective [2+2] photocycloaddition of ethylene to a chiral cyclohexenone was studied in a continuous flow microcapillary reactor. In all cases examined, the microcapillary reactor gave higher conversions and selectivity than the batch system, even after shorter irradiation times. These findings were explained by the superior temperature control, favorable light penetration, and generation of a gas–liquid slug flow with improved mass transfer in the microreactor.

Diastereoselective [2+2] Photocycloaddition of a Chiral Cyclohexenone with Ethylene in a Continuous Flow Microcapillary Reactor

http://www.akademiai.com/content/03163u0p80225v14/?p=bb18d4ec7c044f5c80013806493e8850&pi=2

Authors

Kimitada Terao¹, Yasuhiro Nishiyama¹, Hiroki Tanimoto¹, Tsumoru Morimoto¹, Michael Oelgemöller², Kiyomi Kakiuchi¹ 

^{kakiuchi@ms.naist.jp, http://mswebs.naist.jp/LABs/kakiuchi/member/staff/CV_kakiuchi.pdf}

¹Nara Institute of Science and Technology (NAIST) Graduate School of Materials Science 8916-5 Takayama-cho, Ikoma Nara 630-0192 Japan
²James Cook University School of Pharmacy and Molecular Sciences Townsville QLD 4811 Australia

more………..

http://mswebs.naist.jp/LABs/kakiuchi/achevement/paper.htm

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“Diastereodifferentiating [2+2] Photocycloaddition of Chiral Cyclohexenone Carboxylates with Cyclopentene by a Microreactor”
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J. Photochem. Photobiol. A: Chem. 2012, 242, 13-19.