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DR ANTHONY MELVIN CRASTO, WORLDDRUGTRACKER

Double strike against cancer

 cancer, drugs  Comments Off on Double strike against cancer
Jun 172013
 
Double strike against cancer
13.06.2013 – German researchers have found a way to circumvent chemotherapy resistance in cancer cells.

A new therapeutic approach can take advantage of cancer cells’ need to repair double-strand breaks in DNA, in order to overcome the tumour’s resistance to chemotherapy (Science Transl. Medicine). According to the research group headed by Hans Christian from University Cologne, mutations in the ATM gene protect cancer cells from cell death during chemotherapy. ATM  is instrumental in initiating DNA repair and inducing cell death when repair is not possible in curse of the so-called DNA damage response (DDR).  http://www.eurobiotechnews.eu/news/news/2013-02/double-strike-against-cancer.html

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Silence Starts Phase Ia/IIb Trial of Cancer Drug as It Looks to Balance Pipeline

 cancer  Comments Off on Silence Starts Phase Ia/IIb Trial of Cancer Drug as It Looks to Balance Pipeline
May 302013
 

Silence Starts Phase Ia/IIb Trial of Cancer Drug as It Looks to Balance Pipeline

Silence Starts Phase Ia/IIb Trial of Cancer Drug as It Looks to Balance Pipeline GenomeWeb If no toxicity is observed, the phase IIa arm of the trial will begin with pancreatic cancer patients receiving the two drugs once a week for three consecutive weeks, with no treatment on the fourth week. This dosing schedule will continue in … http://www.genomeweb.com/rnai/silence-starts-phase-iaiib-trial-cancer-drug-it-looks-balance-pipeline

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New Tumor-Killer Shows Great Promise in Suppressing Cancers

 cancer  Comments Off on New Tumor-Killer Shows Great Promise in Suppressing Cancers
May 232013
 

Scientists from Nanyang Technological University (NTU) and Lund University, Sweden, have bioengineered a novel molecule which has been proven to successfully kill tumour cells. (Credit: Image courtesy of Nanyang Technological University)

read all at

http://www.sciencedaily.com/releases/2013/05/130521105604.htm

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